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METABOLIC EDGE

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Metabolic Edge is a potent blend of three natural extracts that is designed to provide optimal weight management as well as blood sugar and lipid control. Current research shows that these extracts activate genes and metabolic pathways, such as AMPK and SlRT, that are activated during times when cellular energy is stressed, such as during fasting exercise and caloric restriction. These mechanisms work together to improve whole body metabolism through increasing:

Thermogenesis (1)

Fat Burning (1)

Metabolic Rate (1)

Insulin Sensitivity & Leptin Sensitivity (2, 3, 6, 8, 11, 13, 28 - 30)

Blood Sugar Control (add)

Mitochondrial Health

Combining 3 Potent Natural Extracts To Fuel Metabolism

Fucoxanthin is a brown pigment found in seaweed that has been shown to cause over 10 lbs of weight loss over 16 weeks in people with obesity in a double-blind, randomized, placebo-controlled study [1].

Metabolic Edge provides over 200% more fucoxanthin than other popular products, making Metabolic Edge the best priced fucoxanthin on the market!

Berberine is a natural alkaloid that has been shown to cause weight loss in a multitude of studies on people with obesity, metabolic syndrome, type 2 diabetes, and women with polycystic ovarian syndrome. In all of these studies, berberine improved weight loss while also improving overall metabolism. (2, 3, 20, 21, 26)

ActivAMP is a heat-treated Jiaogulan extract that has been shown to reduce waistline by 20.9 cm2 in obese adults over 12 weeks in a double-blind, randomized, placebo-controlled study. [27] 

While other heat-treated Jiaogulan Extracts have been shown to cause weight loss [28], ActivAMP is currently the only heat-treated extract on the market.

A New Generation Of

Weight Loss Supplements

Metabolic Edge is part of the next generation of weight loss supplements, that targets genes and metabolic pathways that control metabolic rate and body fat levels [1, 2, 27].

Unlike older weight loss supplements that relied on stimulants to increase metabolism, Metabolic Edge increases metabolism in a stimulant-free way by increasing thermogenesis, the burning of calories to make body heat.[1, 58-67]

 

Metabolic Edge regulates genetics and metabolic pathways in muscles and fat tissue. Starting with the first dose of Metabolic Edge, the enzymes and genes that allow fat tissue to grow and absorb fat and carbohydrates will be inhibited [2]. Because of this, Metabolic Edge directly prevents fat tissue from growing and  dietary fat from being stored with each dose. [68-73]

While Metabolic Edge suppresses the enzymes and genetics that allow fat tissue to absorb calories and grow, it also stimulates the enzymes and genetics necessary to allow muscle tissue to absorb and burn calories.  These effects combined allows Metabolic Edge to shuttle calories away from fat tissue where they would be stored, and instead directs calories to muscle tissue and helps them be burned.

Metabolic Edge even antlers the metabolism of fat tissue, changing it from a fat storing tissue, to a fat burning tissue. After several weeks of continuous usage, the fucoxanthin in Metabolic Edge accumulates selectively in fat tissue [76], reaching a molecular critical mass over time.  At this point, fucoxanthin turns on the fat burning pathways in your fat tissue, literally burning off extra fat as 

heat [1, 58-67].  This process is known as thermogenesis.  Through thermogenesis, fucoxanthin has been shown to increase metabolic rate by ~450 calories per day [1]. Because of this, the benefits of Metabolic Edge improve the longer you take it [1, 76]. 

STOP STORING FAT

START BURNING FAT!

CONTROL WHAT YOUR BODY DOES WITH CALORIES

PROVEN HEALTH BENEFITS IN HUMANS

The following information is based on clinical trials in humans. We at Nutri-Thrive believe in the importance of discerning between health claims based on human clinical trials, and those based on alternative methods.

Human Clinical Trials Show That The Ingredients In

 Metabolic Edge Have Potent Metabolic Benefits:

  • Increase Metabolic Rate (1)

  • Lower Body Fat Percentage (1-3, 20, 21, 26, 27, 28)

  • Inhibit Fat Accumulation (1-3, 20, 21, 26, 27, 28)

  • Improve Blood Sugar Control (4-13, 29, 30)

  • Decrease Total And LDL Cholesterol (4, 5, 7-13, 20, 21, 26)

  • Improve HDL Cholesterol (4, 5, 14,15, 20, 21)

  • Decrease Triglyceride Levels (3, 7-13, 15, 20, 21, 26,  28)

  • Inhibit Genes That Cause Fat Deposition And Development (2)

  • Reduce Liver Fat (1, 28)

  • Improve Insulin Sensitivity (2, 3, 6, 8, 11, 13, 28-31)

  • Improve Levels of Fat Burning Hormones Leptin & Adiponectin (2, 3, 6, 8, 11, 13)

  • Decrease HbA1c (7-13, 30, 31)

  • Anti-Inflammatory (6, 16)

Animal and in vitro Studies

Show Additional Benefits

Impressive results from animal and in vitro studies indicate that the ingredients in Metabolic Edge are:

  • Antioxidant (33-35, 78, 98-100, 102, 137-139, 166-168, 170, 172)

  • Anti-aging (36, 164)

  • Neuroprotective (35, 37, 97-104, 144 151-156)

  • Cancer therapy (112-132, 166-170, 172)

  • Antidepressant (44-46)

  • Adaptogenic (47)

  • Rheumatoid arthritis therapy (40, 135)

  • Improves gut microbiota (48-55)

  • Antiparasitic (24, 38, 133, 134, 162)

  • Increasing Brown Fat (58-67, 166-168, 170, 172-175)

  • prevents fat from being made & stored (68-73)

  • Protects GI tract (94-96)

Works Cited & Links To Studies

PEER REVIEWED HUMAN TRIALS

ANIMAL STUDIES

33. http://www.ncbi.nlm.nih.gov/pubmed/20828602
34. http://www.ncbi.nlm.nih.gov/pubmed/24669227
35. http://www.ncbi.nlm.nih.gov/pubmed/21262264
36. http://www.scirp.org/journal/PaperInformation.aspx?PaperID=21064#.VRirioWgVNQ
37. http://www.ncbi.nlm.nih.gov/pubmed/22563252
38. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103990/
39. http://www.ncbi.nlm.nih.gov/pubmed/8370554
40. http://www.ncbi.nlm.nih.gov/pubmed/24803296
41. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706130/
42. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616265/
43. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616311/
44. http://www.ncbi.nlm.nih.gov/pubmed/18585703
45.http://www.sciencedirect.com/science/article/pii/S0024320507005796
46. http://www.ncbi.nlm.nih.gov/pubmed/17585901
47. http://www.ncbi.nlm.nih.gov/pubmed/23335996
48. http://www.ncbi.nlm.nih.gov/pubmed/22880019
49. http://www.ncbi.nlm.nih.gov/pubmed/21915347
50. http://www.ncbi.nlm.nih.gov/pubmed/24602493
51. http://www.ncbi.nlm.nih.gov/pubmed/20932871
52. http://www.ncbi.nlm.nih.gov/pubmed/21592990
53. http://www.ncbi.nlm.nih.gov/pubmed/21963898
54. http://www.ncbi.nlm.nih.gov/pubmed/22155099
55. http://www.ncbi.nlm.nih.gov/pubmed/25479718
56. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366688/
57. http://www.ncbi.nlm.nih.gov/pubmed/24041461
58. http://www.ncbi.nlm.nih.gov/pubmed/21475918
59. http://www.ncbi.nlm.nih.gov/pubmed/24534841
60. http://www.ncbi.nlm.nih.gov/pubmed/15896707
61. http://www.ncbi.nlm.nih.gov/pubmed/18296336
62. http://www.ncbi.nlm.nih.gov/pubmed/19842104
63. http://www.ncbi.nlm.nih.gov/pubmed/22289788
64. http://www.ncbi.nlm.nih.gov/pubmed/21535684
65. http://www.ncbi.nlm.nih.gov/pubmed/20845386
66. http://www.ncbi.nlm.nih.gov/pubmed/17992001
67. http://www.ncbi.nlm.nih.gov/pubmed/17715888
68. http://www.ncbi.nlm.nih.gov/pubmed/22224971
69. http://www.ncbi.nlm.nih.gov/pubmed/23964316
70. http://www.ncbi.nlm.nih.gov/pubmed/16786166
71. http://www.ncbi.nlm.nih.gov/pubmed/21621511
72. http://www.ncbi.nlm.nih.gov/pubmed/22400485
73. http://www.ncbi.nlm.nih.gov/pubmed/21323331
74. http://www.ncbi.nlm.nih.gov/pubmed/20515643
75. http://www.ncbi.nlm.nih.gov/pubmed/22305278
76. http://www.ncbi.nlm.nih.gov/pubmed/20739451
77. http://link.springer.com/article/10.1007/s12562-008-0018-4#page-1
78. http://www.ncbi.nlm.nih.gov/pubmed/24353833
79. http://www.ncbi.nlm.nih.gov/pubmed/15950219
80. http://www.ncbi.nlm.nih.gov/pubmed/24146106
81. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475273/
82. http://www.ncbi.nlm.nih.gov/pubmed/18798263
83. http://www.ncbi.nlm.nih.gov/pubmed/23857515
84. http://www.ncbi.nlm.nih.gov/pubmed/23118721
85. http://www.ncbi.nlm.nih.gov/pubmed/20558230
86. http://www.ncbi.nlm.nih.gov/pubmed/22732883
87. http://agris.fao.org/agris-search/search.do?recordID=KR2010002794
88. http://www.ncbi.nlm.nih.gov/pubmed/17473531
89. http://www.ncbi.nlm.nih.gov/pubmed/16261522
90. http://www.ncbi.nlm.nih.gov/pubmed/24832985
91. http://www.ncbi.nlm.nih.gov/pubmed/8328423
92. http://www.ncbi.nlm.nih.gov/pubmed/19938216
93. http://en.cnki.com.cn/Article_en/CJFDTOTAL-SYYD200706008.htm
94. http://www.ncbi.nlm.nih.gov/pubmed/17380554
95. http://en.cnki.com.cn/Article_en/CJFDTOTAL-YAOL903.010.htm
96. http://www.ncbi.nlm.nih.gov/pubmed/15330499
97. http://www.ncbi.nlm.nih.gov/pubmed/20104445
98. http://www.ncbi.nlm.nih.gov/pubmed/20819446
99. http://www.ncbi.nlm.nih.gov/pubmed/20428081
100. http://www.ncbi.nlm.nih.gov/pubmed/16806111
101. http://www.ncbi.nlm.nih.gov/pubmed/21897202
102. http://www.ncbi.nlm.nih.gov/pubmed/21459105
103. http://www.ncbi.nlm.nih.gov/pubmed/21333723
104. http://www.ncbi.nlm.nih.gov/pubmed/24223845
105. http://www.ncbi.nlm.nih.gov/pubmed/22576281
106. http://www.ncbi.nlm.nih.gov/pubmed/24832985
107. http://www.ncbi.nlm.nih.gov/pubmed/25992551
108. http://www.ncbi.nlm.nih.gov/pubmed/8732068
109. http://www.ncbi.nlm.nih.gov/pubmed/21665877
110. http://www.ncbi.nlm.nih.gov/pubmed/20702487

in vitro STUDIES

SCIENTIFIC REVIEWS